Thermo Fisher Scientific Claudin 19 Polyclonal Antibody
Claudin 19 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 액상 형태, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Claudin 19, amino acids 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.
Defects in this gene cause hypomagnesemia renal with ocular involvement (HOMGO), a progressive renal disease characterized by magnesium wasting, hypomagnesemia, hypercalciuria, and nephrocalcinosis, associated with ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia, and nystagmus.
Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
[provided by RefSeq, Jun 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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