Thermo Fisher Scientific PTGDR Polyclonal Antibody
인간 Prostaglandin D2 수용체를 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 4-7 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer에 0.1% sodium azide 포함. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 4–7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from 3rd extracellular domain of human Prostaglandin D2 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551466 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon: 100%
- Monkey, Marmoset: 95%
- Dog, Pig: 85%
- Panda, Bovine: 80%
Target Information
The protein encoded by this gene is a G-protein-coupled receptor functioning as a prostanoid DP receptor. Its activity is mediated by G-S proteins that stimulate adenylate cyclase, increasing intracellular cAMP and Ca²⁺ levels. Knockout studies in mice suggest that prostaglandin D2 (PGD2), the ligand of this receptor, acts as a mast cell-derived mediator triggering asthmatic responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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