Thermo Fisher Scientific PTGDR Polyclonal Antibody
Human PTGDR 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 15-20 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 0.1% sodium azide 포함. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 15–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human Prostaglandin D2 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551467 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon (100%)
- Monkey (90%)
- Marmoset (85%)
Target Information
The protein encoded by this gene is a G-protein-coupled receptor functioning as a prostanoid DP receptor. Its activity is mediated by G-S proteins that stimulate adenylate cyclase, leading to increased intracellular cAMP and Ca²⁺. Knockout studies in mice indicate that prostaglandin D2 (PGD2), the ligand of this receptor, acts as a mast cell-derived mediator triggering asthmatic responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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