Thermo Fisher Scientific ZIP10 Polyclonal Antibody
ZIP10 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피 정제, 1 mg/mL 농도. ZIP10은 아연 수송체로 다양한 생물학적 연구에 활용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (IHC) | 2.5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the center of human ZIP10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157030 |
Product Specific Information
A suggested positive control is human spleen tissue lysate.
PA5-21064 can be used with blocking peptide PEP-1178.
Target Information
ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating positive regulation by thyroid hormones. ZIP10 mRNA was also upregulated in invasive and metastatic breast cancer and cell lines, suggesting ZIP10 could serve as a marker for metastatic phenotype and a potential target for novel treatments. At least three isoforms of ZIP10 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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