Thermo Fisher Scientific CX3CL1 Polyclonal Antibody
Human CX3CL1 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ELISA에 사용 가능하며, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 보존제 무첨가로 고순도 제공. CX3CL1/FKN 특이적이며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 – 1:4,000 |
| ELISA | 1:1,000 – 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CX3CL1 protein (Met1–Arg339) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787831 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CX3CL1/FKN.
Target Information
Chemokines are a family of proteins involved in leukocyte trafficking during immune surveillance and inflammation. They are classified by the positions of key cysteine residues.
CX3CL1 is a CX3C chemokine that mediates leukocyte adhesion (membrane-bound form) and migration (soluble form).
Studies suggest CX3CL1 suppresses production of nitric oxide, IL-6, and TNF-α in activated microglia and neuronal cells, indicating a potential neuroprotective role.
Its receptor, CX3CR1, also serves as a co-receptor for HIV-1 and HIV-2 envelope fusion and infection, which can be inhibited by CX3CL1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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