Thermo Fisher Scientific MARCKSL1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MARCKSL1, validated for Western blot. Recognizes C-terminal region (aa 132–160). Predicted cross-reactivity with multiple species. High purity via Protein A and antigen affinity chromatography. Suitable for re...
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 132–160 amino acids from the C-terminal region of human MARCKSL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634253 |
Product Specific Information
Predicted to react with bovine, mouse, rabbit, and rat based on sequence homology.
Target Information
MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein localized to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC).
MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC. It is expressed in various tissues, with highest levels in testis and uterus. MARCKSL1 participates in membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis, and cell adhesion. Additionally, MARCKSL1 regulates Integrin activation and Integrin-dependent signal transduction pathways, particularly those involved in macrophage spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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