Thermo Fisher Scientific OTUB1 Monoclonal Antibody (OTI2H1), TrueMAB
OTUB1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC(P), ICC/IF에 사용 가능. Human 시료에 반응하며, Lyophilized 형태로 제공. 고순도 Affinity chromatography 정제 제품으로 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H1 |
| Immunogen | Full length human recombinant protein of human OTUB1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
- Biotin conjugated format available (Product # TA700424)
- Custom conjugation available upon request
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
OTUB1 is a member of the OTU superfamily of predicted cysteine proteases. It functions as a highly specific ubiquitin iso-peptidase, cleaving ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. OTUB1 interacts with other ubiquitin proteases and E3 ubiquitin ligases that regulate cytokine gene transcription in the immune system. It is implicated in ubiquitin-dependent pathways, possibly serving as an editing enzyme for polyubiquitin chain elongation. Multiple transcript variants are produced through alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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