Thermo Fisher Scientific CD39 Monoclonal Antibody (eBioA1 (A1)), FITC, eBioscience
인간 CD39 단백질을 인식하는 마우스 단클론 항체로, FITC로 표지되어 있습니다. Flow Cytometry에 최적화되어 있으며, 5 µL/test로 사용 가능합니다. CD39 발현 분석 및 면역세포 활성 연구에 적합합니다. 4°C 보관, 동결 금지.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Flow Cytometry (Flow) | 5 µL (0.25 µg)/test | View 19 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBioA1 (A1) |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151149 |
Available Formats
- Unconjugated
- APC
- APC-eFluor 780
- Brilliant UV 805
- NovaFluor Blue 610-70S
- NovaFluor Blue 660-120S
- NovaFluor Blue 690
- NovaFluor Red 700
- NovaFluor Red 725
- NovaFluor Red 755
- NovaFluor Yellow 660
- NovaFluor Yellow 755
- PE
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 702
- Request custom conjugation
Product Specific Information
The eBioA1 monoclonal antibody reacts with human CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) or NTPDase. CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer. It is the most prominent ectoenzyme of the immune system, functioning to remove toxic extracellular ATP by converting it to ADP or AMP. CD39 works together with CD73 to hydrolyze ATP and is well characterized on Langerhans cells.
Expression of CD39 was originally identified on activated lymphocytes and is also found on subsets of T cells, B cells, dendritic cells, and weakly on monocytes and granulocytes. CD39 and CD73 are expressed on regulatory T cells (Treg), facilitating their entry into inflamed areas with high ATP levels. Expression on Foxp3⁺CD4⁺ cells ranges from 25–45%.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated for flow cytometry on normal human peripheral blood cells; use 5 µL (0.25 µg) per test.
Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD39 cell surface antigen (70–100 kDa) is expressed on peripheral blood B cells, monocytes, T cell clones, and weakly on granulocytes. It exhibits ecto-ATPase activity, and its expression is induced on T cells and increased on B cells as a late activation antigen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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