Thermo Fisher Scientific Calreticulin Monoclonal Antibody (7B2)
Calreticulin 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC, Flow Cytometry에 사용 가능. 인간 시료 반응성. 고순도 Protein G 정제, 2 mg/mL 농도, PBS/glycerol buffer로 안정적 보관 가능.
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Thermo Fisher Scientific Calreticulin Monoclonal Antibody (7B2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:250 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7B2 |
| Immunogen | Recombinant full-length protein corresponding to Human Calreticulin (aa 1 to C-terminus) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C for short term; -20°C for long term (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931520 |
Target Information
Calreticulin (Calr) is a calcium-binding chaperone that promotes protein folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. It transiently interacts with monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1, mediating its nuclear export. Calr may also play a role in maternal gene expression regulation and oocyte maturation through calcium homeostasis control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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