Thermo Fisher Scientific CDKN2C Polyclonal Antibody
CDKN2C 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP에 적합하며 인간, 생쥐, 랫트 반응성. 고순도(>95%) 항원 친화 크로마토그래피 정제, 액상 형태로 장기 보관 시 -20°C 권장.
- 판매단위
- pk
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Thermo Fisher Scientific CDKN2C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100–150 of Human p18 INK4c |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2802987 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by this gene belongs to the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 to prevent activation of CDK kinases, thereby regulating cell cycle G1 progression. Overexpression suppresses human cell growth correlated with wild-type RB1 function. Knockout mouse studies indicate roles in spermatogenesis regulation and tumorigenesis suppression. Two alternatively spliced transcript variants encoding identical proteins have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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