Thermo Fisher Scientific Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Monoclonal Antibody (rKRT20/6536)
인간 KRT20 단백질을 인식하는 단클론 항체로, 결장 상피세포 마커로 사용됩니다. 파라핀 및 PFA 고정 조직의 면역조직화학(IHC)에 적합합니다. 단백질 A/G 정제, 액상 형태, 4°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rKRT20/6536 |
| Immunogen | Recombinant fragment of human KRT20 protein (around aa 196–323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for maintaining the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins.
Type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells, specifically expressed in gastric and intestinal mucosa.
Type I cytokeratin genes are clustered in the region of chromosome 17q12–q21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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