Thermo Fisher Scientific Phospho-Claudin 7 (Tyr210) Polyclonal Antibody
Claudin 7 단백질의 Tyr210 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며 Human, Mouse, Rat 시료에 반응. Affinity chromatography로 정제된 액상 형태로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 210 (S-K-E-Y(p)-V) derived from Human Claudin 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554136 |
Product Specific Information
- A suggested positive control for Western blot is NIH-3T3 cells.
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junctions act as physical barriers preventing solutes and water from passing freely through the paracellular space between epithelial or endothelial cells, and play critical roles in maintaining cell polarity and signal transduction.
Differential expression of this gene has been observed in various malignancies, including breast, ovarian, liver, urinary, prostate, lung, head and neck, and thyroid cancers.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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