Thermo Fisher Scientific EphA2 Polyclonal Antibody
EphA2 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, Flow Cytometry에 적합합니다. Human 및 Mouse에 반응하며, 고순도 정제 및 안정적 액상 형태로 제공됩니다. 암 연구 및 세포 신호전달 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | View 1 publication |
| Flow Cytometry (Flow) | 1:10–1:50 | View references |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 30–60 amino acids from the N-terminal region of human EphA2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2099079 |
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors are implicated in developmental events, particularly in the nervous system. EPHA2 is overexpressed in many human cancers. The tyrosine kinase (TK) group regulates cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes have been sequenced, including 58 receptor TKs (EGFR, EPH, FGFR, PDGFR, TRK, VEGFR families) and 32 cytosolic TKs (ABL, FAK, JAK, SRC families).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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