Thermo Fisher Scientific PSMB3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PSMB3 protein. Validated for IHC and ICC/IF applications. High specificity with recombinant protein immunogen. Supplied as liquid, unconjugated form with 0.1 mg/mL concentration. Suitable for research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSMB3. Recombinant protein control fragment (Product #RP-100105). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646061 |
Product Specific Information
- Immunogen sequence:
AMKGKNCVAI AADRRFGIQA QMVTTDFQKI FPMGDRLYIG LAGLATDVQT VAQRLKFRLN LYELKEGRQI KPYTLMSMVA - Highest antigen sequence identity to orthologs:
Mouse – 100%, Rat – 100%
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of 4 rings of 28 non-identical subunits (2 rings of 7 alpha subunits and 2 rings of 7 beta subunits). Proteasomes are distributed throughout eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome plays an essential role in processing class I MHC peptides.
The PSMB3 gene encodes a member of the proteasome B-type family (T1B family), a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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