Thermo Fisher Scientific AMPK gamma-1 Recombinant Rabbit Monoclonal Antibody (5E5)
AMPK gamma-1 단백질을 인식하는 토끼 단클론 항체로, 인간 시료에 반응합니다. IHC(P)와 ELISA에 적합하며, 에너지 대사 조절 연구에 유용합니다. HEK293 세포에서 발현된 재조합 항체로, 고순도 친화 크로마토그래피로 정제되었습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5E5 |
| Immunogen | A synthesized peptide derived from human PRKAG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092712 |
Target Information
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. It is an important energy-sensing enzyme that monitors cellular energy status. Upon activation by metabolic stress, AMPK phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes in fatty acid and cholesterol biosynthesis. This subunit represents one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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