Thermo Fisher Scientific MEKK2 Recombinant Rabbit Monoclonal Antibody (ARC2291)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC2291

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEKK2 (Q9Y2U5) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEKK2,uniProtId:Q9Y2U5-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:619,antigenImageFileName:MA5-37973_MEKK2_Q9Y2U5-1_Rabbit.svg,antigenImageFileNamePDP:MA5-37973_MEKK2_Q9Y2U5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897891

Product Specific Information

Positive Samples: MCF7, Jurkat, Mouse lung

Immunogen sequence: MDDQQALNSI MQDLAVLHKA SRPALSLQET RKAKSSSPKK QNDVRVKFEH RGEKRILQFP RPVKLEDLRS KAKIAFGQSM DLHYTNNELV IPLTTQDDLD

Target Information

MAP3K2 (MEKK2) is a serine/threonine kinase that activates kinases involved in the MAP kinase signaling pathway. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.