Thermo Fisher Scientific Neuroserpin Polyclonal Antibody
Rabbit polyclonal antibody against Neuroserpin for WB, IHC(F), and ICC/IF applications. Synthetic peptide immunogen derived from rat Neuroserpin residues 350–C-terminus. Liquid form, 1 mg/mL concentration, stored at 4°C or -20°C. For research use only.
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- PA519610
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Rat Neuroserpin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984879 |
Product Specific Information
- For Western Blot, this antibody has non-specific bands at 80 kDa.
- This antibody is predicted to react with human based on sequence homology.
Target Information
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in regulating axonal growth and synaptic plasticity. Mutations in this gene cause familial encephalopathy with neuroserpin inclusion bodies (FENIB), a dominantly inherited form of familial encephalopathy and epilepsy characterized by accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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