Thermo Fisher Scientific Neuroserpin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:250

-

Immunohistochemistry (Frozen) (IHC (F))

1 µg/mL

-

Immunocytochemistry (ICC/IF)

1 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Rat Neuroserpin. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Neuroserpin,uniProtId:Q9JLD2-1,ncbiNodeId:10114,antigenRange:350-410,antigenLength:410,antigenImageFileName:PA5-19610_Neuroserpin_Q9JLD2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-19610_Neuroserpin_Q9JLD2-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10984879

Product Specific Information

For Western Blot, this antibody has non-specific bands at 80 kDa.

This antibody is predicted to react with human based on sequence homology.

Target Information

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.