Thermo Fisher Scientific AMOT Monoclonal Antibody (OTI1F11), TrueMAB
AMOT 단백질을 인식하는 Mouse monoclonal 항체로 Western blot에 최적화됨. HEK293T 세포에서 생산된 full-length human recombinant protein을 면역원으로 사용. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F11 |
| Immunogen | Full length human recombinant protein of human AMOT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
AMOT (Angiomotin) belongs to the motin family of angiostatin-binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ-binding motifs.
AMOT plays a central role in maintaining tight junctions through complex formation with ARHGAP17, regulating the uptake of polarity proteins.
It is predominantly expressed in endothelial cells of capillaries and larger vessels of the placenta and may mediate the inhibitory effect of angiostatin on tube formation and endothelial cell migration during angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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