Thermo Fisher Scientific NFKBIL1 Polyclonal Antibody
Rabbit 유래의 NFKBIL1 폴리클로날 항체로 Western Blot에 1:1,000 희석 비율로 사용 가능. 인간 NFKBIL1 펩타이드 면역원으로 제작. 마우스 및 랫트 시료에도 반응 예측. 액상 형태로 -20°C에서 보관하며 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human NFKBIL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691937 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
NF-kappa-B inhibitor-like protein 1 (NFKBIL1), also named Ikb like and IkbL1, is a 381 amino acid member of the inhibitor of NF-kappaB (IkappaB) family of proteins.
NFKBIL1 contains two ANK repeats and is expressed in the rheumatoid synovial lining and sub-lining layers, co-localized in CD68+ and CD3+ cells, but not Factor VIII+ cells.
Defects in NFKBIL1 expression are reported to cause susceptibility to rheumatoid arthritis (RA), a systemic inflammatory autoimmune disease affecting joints.
RA is characterized by inflammatory changes in synovial membranes and articular structures, widespread fibrinoid degeneration of collagen fibers in mesenchymal tissues, and atrophy and rarefaction of bony structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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