Thermo Fisher Scientific TOM70 Polyclonal Antibody
TOM70 단백질을 인식하는 Rabbit Polyclonal 항체로, Human과 Mouse 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS buffer(40% glycerol) 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TOMM70 (aa 383–512). Recombinant protein control fragment (Product #RP-90995). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789666 |
Product Specific Information
Immunogen sequence:
PLLSTQDFNM AADIDPQNAD VYHHRGQLKI LLDQVEEAVA DFDECIRLRP ESALAQAQKC FALYRQAYTG NNSSQIQAAM KGFEEVIKKF PRCAEGYALY AQALTDQQQF GKADEMYDKC IDLEPDNATT
Target Information
Functional mitochondria require up to 1000 proteins to function properly, with 99% synthesized as precursors in the cytoplasm and transported into the mitochondria with the aid of cytosolic chaperones and mitochondrial translocators (import components). Proteins to be imported are chaperoned to the mitochondria by the cytosolic heat shock protein (cHSP70) and are immediately pursued by Translocators of the Outer Membrane (TOMs), followed by transient interactions of the unfolded proteins with Translocators of the Inner Membrane (TIMs).
TOMM70A is ubiquitously expressed in human tissues and localizes in the mitochondria. It may play a significant role in the import of nuclear-encoded mitochondrial proteins with internal targeting sites such as ADP/ATP carriers and uncoupling proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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