Thermo Fisher Scientific LEFTY2 Polyclonal Antibody
LEFTY2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB와 IHC에 적합합니다. 인간 종에 반응하며 N-말단 펩타이드(aa 1–50)를 면역원으로 사용했습니다. 고순도 Affinity Chromatography로 정제된 액상 항체로 연구용에 적합합니다.
- 판매단위
- pk
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Thermo Fisher Scientific LEFTY2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human LEFTY2 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610529 |
Product Specific Information
- Peptide sequence: MWPLWLCWAL WVLPLAGPGA ALTEEQLLGS LLRQLQLSEV PVLDRADMEK
- Sequence homology:
- Cow: 79%
- Horse: 93%
- Human: 100%
- Mouse: 79%
- Pig: 86%
- Rat: 83%
Target Information
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis.
Lefty1 acts as a regulator of Lefty2 and NODAL, as the lack of the former results in bilateral expression of nodal, lefty2, and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness).
Lefty2 may play a role in endometrial bleeding.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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