Thermo Fisher Scientific RASD2 Polyclonal Antibody
RASD2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot, IHC, ICC/IF에서 사용 가능하며, 인간·마우스·랫트 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of the human TEM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152061 |
Product Specific Information
- Suggested positive control: human colon tissue lysate
- PA5-20438 can be used with blocking peptide PEP-0555
Target Information
Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein predominantly expressed in the striatal region of the brain. It belongs to the RASD subfamily of Ras-related GTP-binding proteins and plays a role in brain development and function. Mice lacking this gene show increased anxiety and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes upregulated in tumor endothelium. Tumor endothelial markers are significantly upregulated during angiogenesis and neoangiogenesis, crucial for solid tumor growth. TEMs localized on the cell surface and conserved across species are of interest for anti-angiogenic therapy development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-20438_RASD2_Q96D21-1_Rabbit.svg, PA5-20438_RASD2_Q96D21-1_Rabbit_PDP.jpeg)
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