Thermo Fisher Scientific PLS3 Polyclonal Antibody
Human PLS3 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS 기반 저장 용액에 40% 글리세롤 포함, 연구용으로만 사용.
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Thermo Fisher Scientific PLS3 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PLS3. Recombinant protein control fragment (Product #RP-108067) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662568 |
Product Specific Information
Immunogen sequence:
MDEMATTQISK DELDELKEAF AKVHighest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis.
Members of this family, PLS1 and PLS3, are substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis.
PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3.
Overexpression of PLS3 in HEK293 cells enhances apoptosis induced by UV irradiation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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