Thermo Fisher Scientific VPS51 Polyclonal Antibody
VPS51 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 마우스 시료에 반응합니다. IHC(P) 실험에 적합하며, 고순도의 affinity chromatography 정제 항체입니다. 액상 형태로 PBS buffer에 보존되며 연구용으로 사용됩니다.
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Thermo Fisher Scientific VPS51 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human VPS51 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2688395 |
Product Specific Information
Predicted to react with Mouse samples.
Target Information
VPS51 acts as a component of the GARP complex, which is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
The GARP complex is essential for maintaining protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic, and autophagy.
VPS51 promotes tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN and participates in retrograde transport of acid hydrolase receptors.
Additionally, VPS51 functions as part of the EARP complex, which is involved in endocytic recycling and associates with Rab4-positive endosomes to promote recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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