Thermo Fisher Scientific EDN2 Monoclonal Antibody (3B4-1C5)
인간 EDN2 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합합니다. GST 태그가 결합된 재조합 EDN2 단백질로부터 제작되었으며, 친화 크로마토그래피로 정제되었습니다. PBS(pH 7.4) 용액에 보존되며 방부제는 포함되지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B4-1C5 |
| Immunogen | EDN2 (AAH34393, 1–178 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MVSVPTTWCS VALALLVALH EGKGQAAATL EQPASSSHAQ GTHLRLRRCS CSSWLDKECV YFCHLDIIWV NTPEQTAPYG LGNPPRRRRR SLPRRCQCSS ARDPACATFC LRRPWTEAGA VPSRKSPADV FQTGKTGATT GELLQRLRDI STVKSLFAKR QQEAMREPRS THSRWRKR
Target Information
Endothelins are endothelium-derived vasoconstrictor peptides. Endothelin 2 (ET-2), encoded by the EDN2 gene in humans, is a secreted peptide (~2 kDa, 21 amino acids) derived from the endothelin-2 precursor (~20 kDa). It acts as a ligand for endothelin receptors, modulating various cell signaling pathways. Diseases associated with endothelins include aortic disease and patent ductus arteriosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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