Thermo Fisher Scientific c-myc Polyclonal Antibody, Agarose
Goat polyclonal antibody conjugated to agarose for c-myc tag detection. Suitable for immunoprecipitation applications. High specificity for amino acids 410–419 of human myc. Purified by antigen affinity chromatography. For research use only.
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Thermo Fisher Scientific c-myc Polyclonal Antibody, Agarose
Applications
- Immunoprecipitation (IP)
Tested Dilution: 0.1–1 mg
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Tag |
| Host/Isotype | Goat |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Amino acids 410–419 (EQKLISEEDL) of human myc conjugated to KLH |
| Conjugate | Agarose |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 2–8°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Myc is a proto-oncogene encoding a nuclear phosphoprotein that regulates cell cycle progression, apoptosis, and cellular transformation. The MYC protein forms a heterodimer with MAX, binding to the E-box DNA consensus sequence to control transcription of target genes. Gene amplification is commonly observed in various human cancers. Translocations involving MYC are associated with Burkitt lymphoma and multiple myeloma. Translation may initiate from both an upstream non-AUG (CUG) and downstream AUG start site, producing two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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