Thermo Fisher Scientific c-myc Polyclonal Antibody
Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 사용 가능한 c-Myc 폴리클로날 항체. Goat 유래 비접합형 항체로, Protein A 정제 및 PBS 완충액에 보관. 세포주기 및 암 관련 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:20,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ELISA | 1:10,000–1:30,000 |
| Immunoprecipitation (IP) | 1–4 µg/mg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Tag |
| Host/Isotype | Goat |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Amino acids 410–419 (EQKLISEEDL) of human myc conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage conditions | 2–8°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Myc is a proto-oncogene encoding a nuclear phosphoprotein involved in cell cycle progression, apoptosis, and cellular transformation. The encoded protein forms a heterodimer with the transcription factor MAX, binding to the E-box DNA consensus sequence to regulate transcription of specific target genes. Amplification of this gene is frequently observed in various human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma. Translation may initiate from both an upstream non-AUG (CUG) and a downstream AUG start site, producing two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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