Thermo Fisher Scientific Human C5a Recombinant Protein, PeproTech
인체 C5a 단백질을 재조합 형태로 제공하며, 염증 및 면역 반응 연구에 활용됩니다. E. coli에서 발현된 8.3 kDa 단백질로, ≥98% 순도와 낮은 엔도톡신 함량을 보유합니다. HUVEC 세포 부착 활성 검증 완료, 동결건조 형태로 제공됩니다.
- 카탈로그번호
- 300-70-xxxxx (5개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
5개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human C5a Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to publication (1)
Miscellaneous PubMed (Misc)
- Refer to publications (2)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published species | Human, Mouse |
| Expression System | E. coli |
| Amino acid sequence | TLQKKIEEIA AKYKHSVVKK CCYDGACVNN DETCEQRAAR ISLGPRCIKA FTECCVVASQ LRANISHKDM QLGR |
| Molecular weight | 8.3 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin concentration | <1 EU/µg |
| Activity | Supports adhesion of HUVEC cells to Recombinant Human C5a-coated surface |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient |
Product Specific Information
- Catalog No. 300-70-1MG is provided as 2 × 500 µg (300-70-500UG).
- Recombinant Human C5a is an 8.3 kDa glycoprotein containing 74 amino acid residues of the C5a anaphylatoxin chain.
- Shipped at ambient temperature. For storage, handling, and reconstitution details, refer to the lot-specific Certificate of Analysis.
Target Information
The gene encodes the fifth component of complement (C5), critical in inflammatory and cell-killing processes. It consists of alpha and beta chains linked by a disulfide bridge. Upon cleavage, the activation peptide C5a acts as a potent anaphylatoxin with spasmogenic and chemotactic activity. The C5b fragment forms a complex with C6, initiating the membrane attack complex formation. Mutations in this gene are associated with complement component 5 deficiency, leading to recurrent infections, and have been linked to liver fibrosis and rheumatoid arthritis susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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