Thermo Fisher Scientific LOX Monoclonal Antibody (OTI3C3), TrueMAB
인간 LOX 단백질(아미노산 22-168)에 특이적인 단클론 항체로 ELISA 및 Luminex 분석에 적합. Mouse IgG1 형식이며 액상 형태, 0.5 mg/mL 농도로 제공. Affinity chromatography로 정제되어 안정적인 성능을 보장. 연구용으로만 사용 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:100–1:1,000
Luminex (LUM)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–168 of human LOX produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase that belongs to a heterogeneous family of enzymes oxidizing primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extracellular matrix. LOX is multifunctional, involved in developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it essential for hypoxia-induced metastasis and a promising therapeutic target for preventing and treating metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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