Thermo Fisher Scientific Human MAPKAPK3 (Inactive), His Tag Recombinant Protein

Thermo Fisher Scientific Human MAPKAPK3 (Inactive), His Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, please spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
• For larger sizes, prepare aliquots to minimize freeze/thaw cycles (do not prepare aliquots below 20 µL).
• Never store kinase diluted.
• Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.

Protein Form: Full Length, Recombinant, Inactive

Target Information

MAPKAPK3 acts as an integrative element in mitogen and stress response signaling. It is a mitogen-activated protein kinase (MAP kinase)-activated protein kinase. MAPKAPK3 is activated by growth inducers and stress stimulation of cells. In vitro, ERK, p38 MAP kinase, and Jun N-terminal kinase can phosphorylate and activate MAPKAPK3, indicating its role in integrating multiple signaling pathways.
MAPKAPK3 interacts with, phosphorylates, and represses the activity of E47, a transcription factor involved in tissue-specific gene expression and cell differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.