Thermo Fisher Scientific MRPS15 Polyclonal Antibody
Human MRPS15 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% 글리세롤) 버퍼에 보관됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MRPS15. Recombinant protein control fragment (Product #RP-107547) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663092 |
Product Specific Information
Immunogen sequence:
EQFMKKIVANP EDTRSLEARI IALSVKIRSY EEHLEKHRKD KAHKRYLLMS IDQRKKMLKN LRNTNYDVFE
Highest antigen sequence identity to the following orthologs:
- Mouse: 77%
- Rat: 76%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes where this ratio is reversed.
Mammalian mitoribosomes lack the 5S rRNA found in prokaryotic ribosomes. The proteins comprising the mitoribosome vary significantly across species, making sequence homology recognition difficult.
MRPS15 encodes a 28S subunit protein belonging to the ribosomal protein S15P family. The encoded protein is over twice the size of its E. coli counterpart, with conserved 12S rRNA binding sites. Among small subunit ribosomal proteins, MRPS15 shows the lowest conservation between human and mouse. Pseudogenes for this gene are found on chromosomes 15q and 19q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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