Thermo Fisher Scientific COP1 Polyclonal Antibody
Human COP1 단백질을 인식하는 Goat Polyclonal Antibody로 ICC/IF 및 Flow Cytometry에 적합. 0.5 mg/mL 농도의 액상 시약이며, TBS buffer(pH 7.3)와 0.5% BSA 포함. -20°C 보관, IL1B 및 CASP1 관련 연구에 활용 가능.
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Thermo Fisher Scientific COP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ETLGLSAGPIPGN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932656 |
Product Specific Information
- Expected to recognize isoform 2 (NP_443121.1) only.
- Possible cross-reaction with INCA (GeneID 440068; NP_001007233.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
Caspase inhibitor involved in regulation of procaspase-1/CASP1 activation and proteolytic maturation of pro-interleukin-1 beta (IL1B). Inhibits IL1B release in response to LPS in monocytes and induces NF-kappa-B activation during pro-inflammatory cytokine response. Prevents CASP1 and CASP4 activation, potentially by blocking interaction between CASP1 and RIPK2. [UniProt]
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-141993_COP1_Q5EG05-2_Goat.svg
- PA5-141993_COP1_Q5EG05-2_Goat_PDP.jpeg
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