Thermo Fisher Scientific hnRNP L Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Immunogen sequence:
  AAGGGGGGEN YDDPHKTPAS PVVHIRGLID GVVEADLVEA LQEFGPISYV

• Storage guidance:
  For short-term use, store at 2–8°C up to 1 week.
  For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Predicted homology:
  Cow: 100%
  Dog: 100%
  Guinea Pig: 100%
  Horse: 100%
  Human: 100%
  Mouse: 100%
  Rabbit: 100%
  Rat: 100%

Target Information

Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, are associated with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes. hnRNP L is among the proteins stably associated with hnRNP complexes and plays a major role in the formation, packaging, processing, and function of mRNA. It is present in the nucleoplasm as part of the hnRNP complex but can also be found outside the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm, suggesting hnRNP proteins may also have cytoplasmic functions. Two transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.