Thermo Fisher Scientific Draxin Polyclonal Antibody
Draxin 단백질을 인식하는 Sheep 유래 Polyclonal Antibody로, WB, IHC(F), ICC/IF 등 다양한 응용에 적합합니다. 인간 및 생쥐 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 사용되며, -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Draxin (aa 26–349) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606600 |
Product Specific Information
- In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse Draxin is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of the Wnt signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-48097_Draxin_Q8NBI3-1_Sheep.svg, PA5-48097_Draxin_Q8NBI3-1_Sheep_PDP.jpeg)
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