Thermo Fisher Scientific TLR3 Recombinant Rabbit Monoclonal Antibody (002)
Mouse TLR3/CD283 특이적 Recombinant Rabbit Monoclonal Antibody로 높은 특이성과 민감도를 제공. ELISA 등 연구용에 적합하며, preservative-free 제형으로 안정적. Lot-to-lot 일관성과 동물유래 성분이 없는 생산 시스템 적용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TLR3 Recombinant Rabbit Monoclonal Antibody (002)
Thermo Fisher Scientific TLR3 Recombinant Rabbit Monoclonal Antibody (Clone 002)
Applications
- ELISA (ELISA)
Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 002 |
| Immunogen | Recombinant Mouse TLR3/CD283 protein (Met1–Leu705) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786883 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to rabbit immune repertoire
This antibody specifically recognizes Mouse TLR3/CD283.
Target Information
TLR3 (Toll-like receptor 3, CD283) is a member of the Toll-like receptor family, playing a critical role in pathogen recognition and activation of innate immunity. TLRs recognize pathogen-associated molecular patterns (PAMPs) and mediate cytokine production necessary for effective immune responses.
TLR3 is abundantly expressed in placenta and pancreas, primarily in dendritic cells. It recognizes viral double-stranded RNA (dsRNA), activating NF-κB and type I interferon pathways. TLR3 signaling utilizes TRIF instead of MyD88, leading to IRF-3 activation and inflammatory cytokine induction.
TLR3 contributes to antiviral defense and has been shown to recognize viruses such as Influenza A and West Nile Virus.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.