Thermo Fisher Scientific TIMD4 Recombinant Rabbit Monoclonal Antibody (102)

Applications

• ELISA (ELISA)
  Tested dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened for optimal performance.
Advantages include:

• High specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broad immunoreactivity due to the rabbit immune repertoire

This antibody is specific for Mouse TIM4/TIMD4.

Target Information

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors involved in regulating Th1 and Th2 cell-mediated immunity.
TIM-4, expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, inducing T-cell expansion and cytokine production.
Unlike other TIM family members, TIM-4 lacks a tyrosine phosphorylation signal in its intracellular domain. The TIM-4 gene is linked to asthma susceptibility in mice and humans and may act as a candidate gene for asthma predisposition.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.