Thermo Fisher Scientific CD162 (Selectin P Ligand) Monoclonal Antibody (PSGL1, 1601)
CD162(PSGL-1) 단일클론 항체로 인간 시료에 반응하며, IHC(파라핀) 실험에 최적화됨. 단백질 A/G 정제, PBS 버퍼에 보존. 면역세포 접착 및 이동 연구에 유용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PSGL1, 1601 |
| Immunogen | Recombinant human SELPLG (CD162) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CD162 (PSGL-1) is a 120 kDa homodimer protein expressed on the surface of leukocytes and platelets.
It binds to CD62P (P-selectin), CD62L (L-selectin), and to a lesser extent CD62E (E-selectin).
These interactions are crucial for leukocyte adhesion, rolling, and extravasation.
CD162 is also an important immune marker of T cell exhaustion in chronic viral infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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