Thermo Fisher Scientific GPR61 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:3000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated COOH-terminal amino acids of 432-452 (SDIIMSDSYLRPAASPRLES) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR61,uniProtId:Q9BZJ8-1,ncbiNodeId:9606,antigenRange:432-451,antigenLength:451,antigenImageFileName:PA3-038_GPR61_Q9BZJ8-1_Rabbit.svg,antigenImageFileNamePDP:PA3-038_GPR61_Q9BZJ8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2664682

Product Specific Information

IHC(P) analysis shows positive staining of GPR61 in human pancreatic islets and enteric ganglion.

WB analysis shows GPR61 in glyco-protein enriched fractions from mock transfected or GPR61 overexpressed 293 cells. The GPR61 antiserum showed specific detection of GPR61 over other tested GPRs.

GPR61 exists in different glycosylated forms and can form dimers and oligomers. Consequently it appears as a long smear on WB or is detected at multiple molecular weights.

Target Information

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR61 is a member of this family (subfamily Orphan-A). It has been reported to be expressed in several regions of brain, including caudate, putamen, and thalamus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.