Thermo Fisher Scientific Phospho-Vasopressin Receptor 1B (Thr377, Thr378) Polyclonal Antibody
인간 Vasopressin Receptor 1B의 Thr377/Thr378 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 7TM0367B
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Vasopressin Receptor 1B (Thr377, Thr378) Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human V1B around the phosphorylation site of Thr377/Thr378 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Vasopressin V1B receptor expression has been documented in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
Activating ligands trigger conformational changes that lead to G-protein signaling and downstream effects.
Negative regulation of GPCRs has significant physiological implications and continues to drive pharmacological research for new drug candidates.
Examples of GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 7TM0367B_AVPR1B_P47901-1_Rabbit.svg, 7TM0367B_AVPR1B_P47901-1_Rabbit_PDP.jpeg)
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