Thermo Fisher Scientific CD357 (AITR/GITR) Monoclonal Antibody (YGITR765.4.16), FITC
Mouse GITR(AITR) 인식 단클론 항체로 FITC 형광 표지되어 있음. Flow cytometry 및 IHC에 적합하며 Protein G로 정제됨. PBS/BSA buffer에 보존, 4°C 또는 -20°C에서 안정적 저장 가능.
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Thermo Fisher Scientific CD357 (AITR/GITR) Monoclonal Antibody (YGITR765.4.16), FITC
Applications and Tested Dilution
- Immunohistochemistry (IHC): Assay-dependent
- Flow Cytometry (Flow): 1.0 µg/1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | YGITR765.4.16 |
| Immunogen | Mouse GITR transfectant |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term, store at -20°C avoiding freeze/thaw cycles; store in the dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539317 |
Additional Formats
- Unconjugated (MA1-70089)
- Biotin (MA5-17932)
- PE (MA5-17934)
- Custom conjugation available upon request
Product Specific Information
MA5-17933 targets GITR in FACS and IHC applications and shows reactivity with Mouse samples.
The immunogen used is mouse GITR transfectant.
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as GITR or AITR, is encoded by the TNFRSF18 gene (mapped to 1p36.33).
This receptor is upregulated upon T-cell activation and plays a key role in immunological self-tolerance mediated by CD25(+)CD4(+) regulatory T cells.
Knockout studies in mice suggest its involvement in CD3-driven T-cell activation and apoptosis regulation.
Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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