Thermo Fisher Scientific PSAP Polyclonal Antibody
Western blot, IHC, ICC/IF에 사용 가능한 PSAP 폴리클로날 항체. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 기반, 친화 크로마토그래피 정제. 액상 형태, -20°C 보관, 연구용 전용.
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- PA5102490
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PSAP (Accession P07602), corresponding to amino acid residues E306–E356. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851892 |
Product Specific Information
Antibody detects endogenous levels of total PSAP.
Target Information
PSAP is a highly conserved glycoprotein that serves as a precursor for four cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long, with nearly identical cysteine residue placement and glycosylation sites. Saposins A–D localize primarily to the lysosomal compartment, facilitating the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists as both a secretory and integral membrane protein and exhibits neurotrophic activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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