Thermo Fisher Scientific ATP6V0A4 Polyclonal Antibody
Human ATP6V0A4 단백질을 인식하는 Rabbit Polyclonal Antibody로, 면역조직화학(IHC)에서 1:2,500–1:5,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상형 항체이며, PBS와 40% 글리세롤 버퍼에 보관. 연구용으로만 사용.
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:2,500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ATP6V0A4. Recombinant protein control fragment (Product #RP-103564). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791801 |
Product Specific Information
Immunogen sequence:
NQNQQALKQS FLELTELKYL LKKTQDFFET ETNLADDFFT EDTSGLLELK AVPAYMTGKL
Target Information
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme mediating acidification of intracellular compartments in eukaryotic cells. V-ATPase-dependent acidification is essential for processes such as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase consists of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain contains the ATP catalytic site, while the V0 domain includes five subunits (a, c, c’, c’’, and d). This gene encodes one of four isoforms of the a subunit found in humans and mice. Alternatively spliced transcript variants encoding the same protein have been described.
Mutations in this gene are associated with renal tubular acidosis with preserved hearing.
[provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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