Thermo Fisher Scientific CXCL11 Monoclonal Antibody (08)

Applications

Tested Dilution

• Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200

Product Specifications

Product Specific Information

• This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
• This antibody has specificity for Human I-TAC/CXCL11.

Target Information

Interferon-inducible T-cell alpha chemoattractant (I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas, liver, thymus, spleen, lung, small intestine, placenta, and prostate.
Its molecular weight is 8–11 kDa. I-TAC is also known as CXCL11 and IP-9.
The cytokine regulates calcium release and induces chemotactic response in activated T-cells, acting as the dominant ligand for CXC receptor-3.
The gene contains 4 exons and at least three polyadenylation signals, suggesting cell-specific regulation of expression.
IFN-gamma strongly induces transcription of this gene, which is upregulated in patients with AIDS, dementia, and multiple sclerosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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