Thermo Fisher Scientific TROP2 Monoclonal Antibody (A5E2)
TROP2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 적합. 고순도 Protein G 정제, 2 mg/mL 농도. Human 시료 반응성. 연구용으로 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A5E2 |
| Immunogen | Recombinant protein within human TROP2 aa 1–274/323 (Extracellular) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931433 |
Target Information
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen belongs to a family of type I membrane proteins and functions as a cell surface receptor that transduces intracellular calcium signals. Mutations in the TROP2 gene cause gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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