Thermo Fisher Scientific LILRA3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: LILRA3-transfected 293T
• Predicted reactivity: Rhesus Monkey (91%), Chimpanzee (91%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer (NK) cells.
All LIRs in subfamily B have an inhibitory function (e.g., LILRB1, MIM 604811).
LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (e.g., LILRA1, MIM 604810).
LILRA3, a member of subfamily A, lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.