Thermo Fisher Scientific Ankyrin 1 Polyclonal Antibody
Human Ankyrin 1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IP에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약이며, 1 mg/mL 농도. 세포골격 관련 Ankyrin 단백질 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1831 and 1881 of human Ankyrin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Ankyrins are a family of proteins that link integral membrane proteins to the spectrin-actin cytoskeleton, playing key roles in cell motility, activation, proliferation, contact, and maintenance of specialized membrane domains. Multiple isoforms are expressed in a tissue-specific and developmentally regulated manner.
Ankyrin 1, the prototype of this family, was first discovered in erythrocytes and later found in brain and muscles. Mutations in erythrocytic ankyrin 1 are associated with hereditary spherocytosis. Complex alternative splicing patterns and truncated muscle-specific isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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