Thermo Fisher Scientific alpha-II Spectrin Monoclonal Antibody (3D7)
alpha-II Spectrin 단백질 검출용 Mouse Monoclonal Antibody(3D7)로, WB·IHC·ICC/IF에 적합. 인간, 마우스, 랫, 소 반응성. 단백질 G 정제, PBS+50% glycerol 보존. 연구용 전용 제품.
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Thermo Fisher Scientific alpha-II Spectrin Monoclonal Antibody (3D7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:3,000 |
| Immunohistochemistry (IHC) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D7 |
| Immunogen | Recombinant construct containing the 7th, 8th, 9th repeats of human alpha II spectrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | ~1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 5 mM sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2539492 |
Product Specific Information
This antibody contains enough material to conduct 10 mini-Western blots.
Target Information
SPTAN1 (spectrin alpha chain, non-erythrocytic 1) belongs to the spectrin family of filamentous cytoskeletal proteins. These proteins serve as essential scaffolds that stabilize the plasma membrane and organize intracellular organelles. Spectrins consist of alpha and beta dimers forming tetramers in a head-to-head arrangement.
SPTAN1 is also involved in DNA repair and cell cycle regulation. Mutations in this gene cause early infantile epileptic encephalopathy-5. Alternative splicing leads to multiple transcript variants.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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