Thermo Fisher Scientific Calpain 13 Polyclonal Antibody
Human Calpain 13에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20–1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 40% glycerol 포함. 연구용으로만 사용하며 장기 보관 시 -20°C 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Calpain 13. Recombinant protein control fragment (Product #RP-91753) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639245 |
Product Specific Information
- Immunogen sequence:
ISRELLHLVT LRYSDSVGRV SFPSLVCFLM RLEAMAKTFR NLSKDGKGLY LTEMEWMSLV MYN - Highest antigen sequence identity to orthologs:
- Mouse: 79%
- Rat: 78%
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large catalytic subunits and a common small regulatory subunit.
This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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