Thermo Fisher Scientific Factor XIII A Polyclonal Antibody
인체 반응성 Factor XIII A 단백질을 인식하는 염소 유래 폴리클로날 항체. Western blot에 최적화되어 있으며, 고순도(암모늄 황산 침전)로 정제됨. 액상 형태로 제공되며 TBS 버퍼에 0.5% BSA와 0.02% sodium azide 포함. -20°C 보관.
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Applications
- Western Blot (WB): 0.05–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HRKLIASMSSDSLRH) corresponding to internal amino acids of F13A1 (aa 703–718) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10981655 |
Product Specific Information
- Predicted to react with mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
The F13A1 gene encodes the coagulation factor XIII A subunit, the final zymogen activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer of two A subunits (catalytic) and two B subunits (carrier). Platelet factor XIII consists only of two A subunits. Upon activation by thrombin and calcium, plasma factor XIII releases its B subunits to form active factor XIIIa, a transglutaminase that stabilizes fibrin clots by crosslinking fibrin molecules and other proteins such as fibronectin.
Factor XIII deficiency can lead to bleeding disorders, impaired wound healing, and habitual abortion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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