Thermo Fisher Scientific KV1.1 (KCNA1) Polyclonal Antibody
KCNA1 단백질을 인식하는 Rabbit Polyclonal 항체로 인간, 마우스, 랫트에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도의 Affinity chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관하며 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCNA1 (Accession Q09470), corresponding to amino acid residues E420–Q470 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852070 |
Product Specific Information
Antibody detects endogenous levels of total KCNA1.
Target Information
This gene encodes a voltage-gated delayed potassium channel related to the Drosophila Shaker channel. The encoded protein has six transmembrane segments, with the S5–S6 loop forming the pore and containing the conserved selectivity filter motif. The functional channel forms a homotetramer. The N-terminus associates with beta subunits that modify inactivation properties and expression levels, while the C-terminus interacts with PDZ domain proteins for channel targeting. Mutations in this gene are associated with myokymia with periodic ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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